Metformin Denk Dosage & Drug Information

Concise Prescribing Info

Contents

Metformin HCl

Indications/Uses

NIDDM.

Dosage/Direction for Use

Initially, 1-2 (500-mg tab) or 1 (850-mg tab) daily. Dose may be increased at intervals of several days up to 2 wk. Max dose: 3 g/day.

Administration

Should be taken with food.

Contraindications

Impaired liver & kidney function, acetonuria, pre-coma, diabetic coma, CV function disorders, resp insufficiency, hypoxic conditions, diabetic retinopathy, catabolic conditions, severe chronic or acute infections, alcoholism.

Special Precautions

Monitoring of renal & liver function regularly. Interrupt during surgery. Pregnancy & lactation. IDDM.

Adverse Reactions

Nausea, vomiting, stomachache, flatulence, wt loss, diarrhoea, metallic taste. Occasionally, headache, dizziness & tiredness.

View ADR Monitoring Form

Drug Interactions

May cause hypoglycemia w/ insulin, oral antidiabetics, salicylates & pyrazolones, MAOIs, oxytetracycline, ACE inhibitors, fibrates, cyclophosphamide & derivatives, β-blockers, clonidine, reserpine & guanethidine. Risk of lactic acidosis increased w/ alcohol & cimetidine. May impair absorption of vit B₁₂. Anticoagulants.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes.

Regulatory Classification

P₁S₁S₃

Presentation/Packing

Form

Metformin Denk film-coated tab 500 mg

Packing/Price

10 × 10's

Form

Metformin Denk film-coated tab 850 mg

Packing/Price

10 × 10's

Metformin Denk

metformin

Manufacturer:

Denk Pharma

Distributor:

Star Medical Supplies